“Brain diseases, including neurodegenerative diseases and neuropsychiatric disorders, have been a major public health problem.
There is no drug that can completely reverse the progression without side effects, whereas PBMT has been demonstrated to be capable of delaying the progression of disability, promoting brain function recovery, and reducing the frequency of relapses.”
“Low-level laser therapy leads to a reduction in inflammatory immune cells, including TH1 and TH17, inhibits inflammation, and augments brain tissue regeneration.”
“Patients saw benefit often within four treatments and resolution of depressive symptoms occurred within 4 weeks for some.”
“PBMT can be classified as strongly recommended for moderate grade of major depressive disorder (MDD) and recommended for anxiety disorder.”
“This systematic review clearly demonstrates the therapeutic role of PBM combined therapies, as well as their potential to improve treatment efficacy and reduce side effects across a wide range of central and peripheral neurological disorders.”
“Near-infrared II photobiomodulation could offer a noninvasive and low-risk adjunctive therapy for stroke injury.”
Near-Infrared II Photobiomodulation Preconditioning Ameliorates Stroke Injury via Phosphorylation of eNOS
Journal: Stroke, 2024 (American Heart Association)
“Infrared photobiomodulation embodies a remarkable and powerful tool for influencing mitochondrial function, inflammation, perfusion, and tissue repair mechanisms in the brain and other tissues.”
“There was significant improvement after 12 weeks of PBM. Increased function, better sleep, fewer angry outbursts, less anxiety, and wandering were reported post-PBM. There were no negative side effects.”
“PBM has shown potential to halt or even reverse the progression of AD, as evidenced by improvements in cognitive impairment and memory across various published studies.”
“Simultaneous intranasal and transcranial PBM (itPBM) is emerging as a possible treatment for cognitive and psychological sequelae of brain injury with evidence of remote effects on other body systems.”
“A total of eleven randomized controlled trials was included in this meta-analysis, and the combined data suggest that PBM may be an efficacious depression treatment.”
“Transcranial photobiomodulation has demonstrated its value as a treatment for neurological and neurodegenerative conditions, including Alzheimer’s disease.”
“Transcranial photobiomodulation may help the brain switch from a state of mind-wandering (DMN) to a state of focused attention (salience and central executive networks) more readily.”