Oncology

“Photodynamic therapy (PDT) has been used as an anti-tumor treatment method for a long time and photosensitizers (PS) can be used in various types of tumors.

Various novel PDT approaches have been studied and developed over the last decades in order to be used against tumors. Preclinical and clinical applications of PDT and PDD have yielded promising results. Topical and systemic administrations of PSs have been utilized in the clinical setting.

In addition, several PDT approaches have been approved by major regulatory bodies including the FDA in the United States and the European Medicines Agency (EMA) in Europe.”

Photodynamic Therapy for the Treatment and Diagnosis of Cancer–A Review of the Current Clinical Status

Journal: Frontiers in Chemistry 2021

 

“PBMT had also been shown to ameliorate muscle atrophy through enhancing PI3K/AKT pathway to suppress MAFbx and MuRF-1 expression

 

Photobiomodulation therapy moderates cancer cachexia-associated muscle wasting through activating PI3K/AKT/FoxO3a pathway

 

Journal: Apoptosis 2024

 

“Patients submitted to PBMT reported better QoL at the end of the treatment compared with the control group. PBMT used for the management of OM preserves the QoL of patients with head and neck cancer.”

 

Impact of Photobiomodulation for prevention of oral mucositis on the quality of life of patients with head and neck cancer: a systematic review

Journal: Lasers in Medical Science 2024