“Photodynamic therapy (PDT) has been used as an anti-tumor treatment method for a long time and photosensitizers (PS) can be used in various types of tumors.
Various novel PDT approaches have been studied and developed over the last decades in order to be used against tumors. Preclinical and clinical applications of PDT and PDD have yielded promising results. Topical and systemic administrations of PSs have been utilized in the clinical setting.
In addition, several PDT approaches have been approved by major regulatory bodies including the FDA in the United States and the European Medicines Agency (EMA) in Europe.”
“PBMT had also been shown to ameliorate muscle atrophy through enhancing PI3K/AKT pathway to suppress MAFbx and MuRF-1 expression
“Patients submitted to PBMT reported better QoL at the end of the treatment compared with the control group. PBMT used for the management of OM preserves the QoL of patients with head and neck cancer.”